Article
Mutagenicity of the agriculture pesticide chlorothalonil assessed by somatic mutation and recombination test in Drosophila melanogaster.
Environmental and molecular mutagenesis - 1 Oct 2024
Veber Bruno, do Amaral Flores Mariana, Lehmann Mauricio, da Rosa Carlos Eduardo, Hoff Mariana Leivas Müller
Abstract excerpt
Chlorothalonil (CTL) is a pesticide widely used in Brazil, yet its mutagenic potential is not fully determined. Thus, we assessed the mutagenicity of CTL and its bioactivation metabolites using the somatic mutation and recombination test (SMART) in Drosophila melanogaster, by exposing individuals, with basal and high bioactivation capacities (standard and high bioactivation cross offspring, respectively), from...
Topics
- Animals
- Drosophila melanogaster
- Nitriles
- Male
- Mutagenicity Tests
- Mutagens
- Female
- Mutation
- Lipid Peroxidation
- Reactive Oxygen Species
- Recombination, Genetic
- Pesticides
- Oxidative Stress