Article
Analysis of hepatitis C virus core encoding sequences in chronically infected patients reveals mutability, predominance, genetic history and potential impact on therapy of Cuban genotype 1b isolates.
European review for medical and pharmacological sciences - 1 Nov 2011
González-Horta E E, Marante J, Amador-Cañizares Y, Alvarez-Lajonchere L, Guerra I, Martínez-Donato G, Dueñas-Carrera S
Abstract excerpt
BACKGROUND AND OBJECTIVES: Hepatitis C virus (HCV) genotypes are relevant to epidemiological questions, vaccine development, and clinical management of chronic HCV infection. In the present work, we aimed at investigating HCV genotype, variability and genetic history of HCV isolates in Cuba from a sample of chronically infected patients. MATERIAL AND METHODS: A prospective study, involving 73 Cuban anti-HCV...
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