Article
Vitamin D receptor gene variants and clinical outcomes after androgen-deprivation therapy for prostate cancer.
World journal of urology - 1 Apr 2013
Pao Jiunn-Bey, Yang Ying-Pi, Huang Chun-Nung, Huang Shu-Pin, Hour Tzyh-Chyuan, Chang Ta-Yuan, Lan Yu-Hsuan, Lu Te-Ling, Lee Hong-Zin, Juang Shin-Hun, Huang Chao-Yuan, Bao Bo-Ying
Abstract excerpt
PURPOSE: Molecular epidemiology studies have shown that vitamin D receptor (VDR) gene polymorphisms are associated with prostate cancer risk. However, the prognostic value of these polymorphisms on clinical outcomes in prostate cancer patients receiving androgen-deprivation therapy (ADT) has not been determined. METHODS: We evaluated the association of five common VDR polymorphisms, ApaI, Tru9I, BsmI, FokI, and...
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