Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Soluble klotho and autosomal dominant polycystic kidney disease.

Clinical journal of the American Society of Nephrology : CJASN - 1 Feb 2012

Pavik Ivana, Jaeger Philippe, Ebner Lena, Poster Diane, Krauer Fabienne, Kistler Andreas D, Rentsch Katharina, Andreisek Gustav, Wagner Carsten A, Devuyst Olivier, Wüthrich Rudolf P, Schmid Christoph, Serra Andreas L

Abstract excerpt

BACKGROUND AND OBJECTIVES: Fibroblast growth factor 23 (FGF23) levels are elevated in patients with autosomal dominant polycystic kidney disease (ADPKD) and X-linked hypophosphatemia (XLH), but only the latter is characterized by a renal phosphate wasting phenotype. This study explored potential mechanisms underlying resistance to FGF23 in ADPKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: FGF23 and klotho...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Familial Hypophosphatemic Rickets
Share to Fibroblast Growth Factor-23

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Kidney Tubules

Share to Klotho Proteins

Share to Least-Squares Analysis

Share to Polycystic Kidney, Autosomal Dominant

Share to Switzerland

Source

Open in PubMed Open full text

Identifiers

PMID: 22193235
DOI: 10.2215/CJN.09020911
PMCID: PMC3280025

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Soluble klotho and autosomal dominant polycystic kidney disease.PMID 22193235Read ↗

Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.Semantic proximity Read ↗

Assessing the Risk of Progression to Kidney Failure in Patients With Autosomal Dominant Polycystic Kidney Disease.Semantic proximity Read ↗

PKD1 Truncating Mutations Accelerate eGFR Decline in Autosomal Dominant Polycystic Kidney Disease Patients.Semantic proximity Read ↗

Latest findings in phosphate homeostasis.Semantic proximity Read ↗

Interactions between FGF23 and Genotype in Autosomal Dominant Polycystic Kidney Disease.Semantic proximity Read ↗

Potentially modifiable factors affecting the progression of autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23) -mediated regulation of systemic phosphate homeostasis.Semantic proximity Read ↗

Central role of the proximal tubular αKlotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism.Semantic proximity Read ↗

Early renal abnormalities in autosomal dominant polycystic kidney disease.Semantic proximity Read ↗

Kidney Measurement and Glomerular Filtration Rate Evolution in Children With Polycystic Kidney DiseaseSemantic proximity Read ↗

Rapid Progression of Autosomal Dominant Polycystic Kidney Disease: Urinary Biomarkers as PredictorsSemantic proximity Read ↗

Distinct phenotype of kidney stone formers with renal phosphate leak.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.