Article
Polymorphisms in the brain-derived neurotrophic factor gene influence memory and processing speed one month after brain injury.
Journal of neurotrauma - 10 Apr 2012
McAllister Thomas W, Tyler Anna L, Flashman Laura A, Rhodes C Harker, McDonald Brenna C, Saykin Andrew J, Tosteson Tor D, Tsongalis Gregory J, Moore Jason H
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) plays a role in cognition, as well as neural survival and plasticity. There are several common polymorphisms in the BDNF gene, one of which (rs6265) is an extensively studied non-synonymous coding polymorphism (Val66Met) which has been linked to cognitive performance in healthy controls and some clinical populations. We hypothesized that the Met allele of rs6265 would be...
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