Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional and In Silico Assessment of GDF3 Gene Variants in a Chinese Congenital Scoliosis Population.

Medical science monitor : international medical journal of experimental and clinical research - 8 May 2018

Chen Jia, Li Xiaoxin, Niu Yuchen, Wu Zhihong, Qiu Guixing

Abstract excerpt

BACKGROUND The present study aimed to evaluate the pathogenicity of 5 [i]GDF3[/i] gene variations using functional and [i]in silico[/i] assessment approaches in a Chinese congenital scoliosis population. MATERIAL AND METHODS We selected 13 patients carrying 5 variants from a congenital scoliosis cohort. The PCR products of samples were verified by Sanger sequencing. The data and sequence alignment were analyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to DNA Mutational Analysis

Share to Genes, Reporter

Share to Luciferases

Share to Scoliosis

Share to Structural Homology, Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 29735971
DOI: 10.12659/MSM.910232
PMCID: PMC5978024

Genes

GDF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional and In Silico Assessment of GDF3 Gene Variants in a Chinese Congenital Scoliosis Population.PMID 29735971Read ↗

Landscape of Secondary Findings in Chinese Population: A Practice of ACMG SF v3.0 ListSemantic proximity Read ↗

Epidemiological survey of idiopathic scoliosis and sequence alignment analysis of multiple candidate genes.Semantic proximity Read ↗

Identification of novel FBN1 variations implicated in congenital scoliosis.Semantic proximity Read ↗

Genetics and pathogenesis of idiopathic scoliosisSemantic proximity Read ↗

In Silico Genetics: Identification of pathogenic nsSNPs in human <i>STAT3</i> gene associated with Job’s syndromeSemantic proximity Read ↗

Diagnostic yield and clinical impact of exome sequencing in early-onset scoliosis (EOS).Semantic proximity Read ↗

Mutation Spectrum analysis of ITGA3 gene associated with Nephrotic syndromeSemantic proximity Read ↗

Screening of known disease genes in congenital scoliosisSemantic proximity Read ↗

Analysis of single nucleotide polymorphism in adolescent idiopathic scoliosis in Korea: for personalized treatment.Semantic proximity Read ↗

The Mutational Landscape of PTK7 in Congenital Scoliosis and Adolescent Idiopathic Scoliosis.Semantic proximity Read ↗

Novel GZF1 pathogenic variants identified in two Chinese patients with Larsen syndrome.Semantic proximity Read ↗

[Analysis of a case of Multiple pterygium syndrome due to a novel variant of CHRNG gene].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.