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Article

NRAS mutation status is an independent prognostic factor in metastatic melanoma.

Cancer - 15 Aug 2012

Jakob John A, Bassett Roland L, Ng Chaan S, Curry Jonathan L, Joseph Richard W, Alvarado Gladys C, Rohlfs Michelle L, Richard Jessie, Gershenwald Jeffrey E, Kim Kevin B, Lazar Alexander J, Hwu Patrick, Davies Michael A

Abstract excerpt

BACKGROUND: There is a need for improved prognostic markers in melanoma. In this study, the authors tested the prognostic significance and clinicopathologic correlations of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) and neuroblastoma RAS viral (v-ras) oncogene homolog (NRAS) mutations in patients with metastatic melanoma. METHODS: Clinical and pathologic data were collected retrospectively on melanoma...

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Source

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Identifiers

PMID: 22180178
DOI: 10.1002/cncr.26724
PMCID: PMC3310961

Genes

NRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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