Article
NRAS mutant melanoma: biological behavior and future strategies for therapeutic management.
Oncogene - 20 Jun 2013
Fedorenko I V, Gibney G T, Smalley K S M
Abstract excerpt
The recent years have seen a significant shift in the expectations for the therapeutic management of disseminated melanoma. The clinical success of BRAF targeted therapy suggests that long-term disease control may one day be a reality for genetically defined subgroups of melanoma patients. Despite this progress, few advances have been made in developing targeted therapeutic strategies for the 50% of patients...
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