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Article

Detection of PAX8-PPARG fusion transcripts in archival thyroid carcinoma samples by conventional RT-PCR.

Genes, chromosomes & cancer - 1 Apr 2012

Klemke Markus, Drieschner Norbert, Belge Gazanfer, Burchardt Käte, Junker Klaus, Bullerdiek Jörn

Abstract excerpt

The t(2;3)(q13;p25) occurs in a subgroup of follicular-patterned thyroid tumors and leads to a fusion of the genes encoding for the thyroid-specific transcription factor paired box 8 (PAX8) and the peroxisome proliferator-activated receptor gamma (PPARγ). Although initially discovered in follicular carcinomas (FTC), the fusion transcripts were also detected in a small fraction of follicular adenomas and rarely in...

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Source

Identifiers

PMID: 22179975
DOI: 10.1002/gcc.21925

Genes

PAX8
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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