Article
PAX8-PPARgamma rearrangement is frequently detected in the follicular variant of papillary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism - 1 Jan 2006
Castro P, Rebocho A P, Soares R J, Magalhães J, Roque L, Trovisco V, Vieira de Castro I, Cardoso-de-Oliveira M, Fonseca E, Soares P, Sobrinho-Simões M
Abstract excerpt
CONTEXT: The clinicopathological characteristics and the molecular features of the follicular variant of papillary thyroid carcinoma (FVPTC) remain controversial. OBJECTIVE/DESIGN/PATIENTS: In an attempt to clarify such controversies and to find whether or not FVPTC cases share the molecular features of follicular tumors, we searched for the presence of PAX8-PPARgamma rearrangements, RAS mutations, and RAP-1,...
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