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Preimplantation genetic diagnosis for inherited breast cancer: first clinical application and live birth in Spain.

Familial cancer - 1 Jun 2012

Ramón Y Cajal Teresa, Polo Ana, Martínez Olga, Giménez Carles, Arjona César, Llort Gemma, Bassas Lluís, Viscasillas Pere, Calaf Joaquin

Abstract excerpt

Carriers of a mutation in BRCA1/2 genes confront a high lifetime risk of breast and ovarian cancer and fifty percent probability of passing the mutation to their offspring. Current options for risk management influence childbearing decisions. The indications for preimplantation genetic diagnosis (PGD) have now been expanded to include predisposition for single-gene, late-onset cancer but few cases have been...

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Source

Identifiers

PMID: 22179695
DOI: 10.1007/s10689-011-9497-z

Genes

PGD
BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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