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Article

EGFR-mediated G1/S transition contributes to the multidrug resistance in breast cancer cells.

Molecular biology reports - 1 May 2012

Chen Shu-Jun, Luan Jing, Zhang Hai-Shi, Ruan Can-Ping, Xu Xin-Yun, Li Qing-Quan, Wang Nian-Hong

Abstract excerpt

Despite the improvement of strategies against cancer therapy, the multidrug resistance (MDR)is the critical problem for successful cancer therapy. Recurrent cancers after initial treatment with chemotherapy are generally refractory to second treatments with these anticancer therapies. Therefore, it is necessary to elucidate the therapy-resistant mechanism for development of effective therapeutic modalities...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22179693
DOI: 10.1007/s11033-011-1347-4

Genes

EGFR

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