Article
Treatment of the bone marrow failure in Fanconi anemia patients with danazol.
Blood cells, molecules & diseases - 15 Feb 2012
Scheckenbach Kathrin, Morgan Mary, Filger-Brillinger Judith, Sandmann Matthias, Strimling Bruce, Scheurlen Wolfram, Schindler Detlev, Göbel Ulrich, Hanenberg Helmut
Abstract excerpt
More than 90% of Fanconi anemia (FA) patients experience progressive bone marrow failure during life with a median onset at 8 years of age. As matched sibling donor transplantation as preferred treatment is not available for the majority of patients, several synthetic androgens have been used as short-term treatment options for the marrow failure in FA patients for more than 50 years. Here, we retrospectively...
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