Article
Alpha 1-antitrypsin granules in the liver--always important?
The Quarterly journal of medicine - 1 Jul 1990
Brind A M, Bassendine M F, Bennett M K, James O F
Abstract excerpt
We have studied the clinical histories and liver biopsy findings in 1951 consecutive adult patients with suspected chronic liver disease, and in four known PiZ-homozygous alpha 1-antitrypsin-deficient patients with emphysema (candidates for lung transplant) and no known liver disease, in order to assess the importance of periportal alpha 1-antitrypsin granules in the liver and their possible causal role in liver...
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