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Linking PharmGKB to phenotype studies and animal models of disease for drug repurposing.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2012

Hoehndorf Robert, Oellrich Anika, Rebholz-Schuhmann Dietrich, Schofield Paul N, Gkoutos Georgios V

Abstract excerpt

The investigation of phenotypes in model organisms has the potential to reveal the molecular mechanisms underlying disease. The large-scale comparative analysis of phenotypes across species can reveal novel associations between genotypes and diseases. We use the PhenomeNET network of phenotypic similarity to suggest genotype-disease association, combine them with drug-gene associations available from the PharmGKB...

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PMID: 22174294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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