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Article

Novel multiplex primer extension and denaturing high-performance liquid chromatography for genotyping of the deafness gene mutations.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Nov 2011

Men Meichao, Xue Jinjie, Jiang Lu, Wang Honghan, Pan Qian, Feng Yong

Abstract excerpt

OBJECTIVE: To find a rapid and accurate genotyping method for specific non-syndromic hearing loss (NSHL)-causing gene mutations for disease diagnosis in different ethnic populations. METHODS: We performed a novel multiplex primer extension (PE) reaction in combination with denaturing high-performance liquid chromatography (DHPLC) to simultaneously detect and genotype the 6 most common mutations in 180 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22169721
DOI: 10.3969/j.issn.1672-7347.2011.11.008

Genes

GJB2

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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