Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two novel STK11 mutations in three Chinese families with Peutz-Jeghers syndrome.

Chinese medical journal - 5 Jul 2007

Zuo Ya-gang, Xu Ke-jian, Su Bin, Ho Michael G, Liu Yue-hua

Abstract excerpt

BACKGROUND: Peutz-Jeghers syndrome (PJS) is an autosomal dominantly inherited disease. STK11/LKB1 gene germline mutations have been identified as responsible for PJS. In our study, we investigated the molecular basis of PJS and evaluated correlation between the STK11 mutations and the Chinese population. METHODS: We collected three pedigrees of PJS and screened the 9 exons and their flanking intronic sequences of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinase Kinases
Share to Child
Share to STK11 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Pedigree

Share to Peutz-Jeghers Syndrome

Share to Protein Serine-Threonine Kinases

Source

Identifiers

PMID: 17637250

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two novel STK11 mutations in three Chinese families with Peutz-Jeghers syndrome.PMID 17637250Read ↗

Analysis of STK11 gene variant in five Chinese patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel mutation in STK11 gene is associated with Peutz-Jeghers syndrome in Chinese patients.Semantic proximity Read ↗

Two novel mutations and a new STK11/LKB1 gene isoform in Peutz-Jeghers patients.Semantic proximity Read ↗

Three novel mutations of STK11 gene in Chinese patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Indian patients.Semantic proximity Read ↗

Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers syndrome.Semantic proximity Read ↗

Novel and recurrent mutations of STK11 gene in six Chinese cases with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A De Novo mutation of STK11 gene in a Chinese patient with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel pathogenic splice site variation in STK11 gene results in Peutz-Jeghers syndrome.Semantic proximity Read ↗

Detection and analysis of common pathogenic germline mutations in Peutz-Jeghers syndrome.Semantic proximity Read ↗

A 23-Nucleotide Deletion in STK11 Gene Causes Peutz-Jeghers Syndrome and Malignancy in a Chinese Patient Without a Positive Family History.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.