Article
Use of cell study models to confirm the weak ABO phenotypes caused by point mutations among Taiwanese.
Annals of clinical and laboratory science - 1 Jan 2011
Chen Ding-Ping, Tseng Ching-Ping, Wang Wei-Ting, Sun Chien-Feng
Abstract excerpt
Numerous phenotypes with serologically weak expression of A or B antigen have been found on the surface of red blood cells. Some of these alleles have mutation(s) in the ABO gene coding sequence; most of the mutations are single-nucleotide substitutions leading to an amino acid change. However, these mutated ABO alleles leading to attenuated antigen expression are not well defined. In this study, the cDNAs for...
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