Autosomal dominant Parkinson's disease.

Abstract excerpt

Over the past two decades the understanding and classification of Parkinson's disease (PD) has been revolutionized by genetic research. Currently, sixteen PARK loci have been identified with autosomal dominant genes such as SNCA, and LRRK2, and autosomal recessive genes such as PRKN, DJ-1, and PINK1. Among these genes, LRRK2 is the most prevalent. Additionally, susceptibility variants located on some of these...

Topics

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• PINK1 gene
• SNCA gene
• VPS35 gene
• Genes, Dominant
• Mutation
• Parkinson's Disease Mechanisms and Treatments