Article
Immortalization of bone marrow-derived porcine mesenchymal stem cells and their differentiation into cells expressing cardiac phenotypic markers.
Journal of tissue engineering and regenerative medicine - 1 Aug 2012
Moscoso Isabel, Rodriguez-Barbosa Jose-Ignacio, Barallobre-Barreiro Javier, Anon Patricia, Domenech Nieves
Abstract excerpt
Mesenchymal stem cells (MSCs) may be among the first stem cell types to be utilized in the clinic for cell therapy, because of their ease of isolation and extensive differentiation potential. Using a porcine model, we have established several cell lines from MSCs to facilitate in vitro and in vivo studies of their potential use for cellular therapy. Bone marrow-derived primary MSCs were immortalized using the...
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