Pancreatic cancer: <i>Helicobacter pylori</i> colonization, <i>N</i>‐Nitrosamine exposures, and ABO blood group

Abstract excerpt

Thirty years of research with animal models has shown that pancreatic adenocarcinoma is induced by N-nitrosamine carcinogens, which damage DNA through adduct formation. Human risk factors for pancreatic cancer include gastric colonization by Helicobacter pylori, as well as dietary intake of those same N-nitrosamines or of nitrite which forms those N-nitrosamines in the stomach, and cigarette smoking which also...

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