Article
Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium.
Cancer research - 1 Feb 2010
Wolpin Brian M, Kraft Peter, Gross Myron, Helzlsouer Kathy, Bueno-de-Mesquita H Bas, Steplowski Emily, Stolzenberg-Solomon Rachael Z, Arslan Alan A, Jacobs Eric J, Lacroix Andrea, Petersen Gloria, Zheng Wei, Albanes Demetrius, Allen Naomi E, Amundadottir Laufey, Anderson Garnet, Boutron-Ruault Marie-Christine, Buring Julie E, Canzian Federico, Chanock Stephen J, Clipp Sandra, Gaziano John Michael, Giovannucci Edward L, Hallmans Göran, Hankinson Susan E, Hoover Robert N, Hunter David J, Hutchinson Amy, Jacobs Kevin, Kooperberg Charles, Lynch Shannon M, Mendelsohn Julie B, Michaud Dominique S, Overvad Kim, Patel Alpa V, Rajkovic Aleksandar, Sanchéz Maria-José, Shu Xiao-Ou, Slimani Nadia, Thomas Gilles, Tobias Geoffrey S, Trichopoulos Dimitrios, Vineis Paolo, Virtamo Jarmo, Wactawski-Wende Jean, Yu Kai, Zeleniuch-Jacquotte Anne, Hartge Patricia, Fuchs Charles S
Abstract excerpt
A recent genome-wide association study (PanScan) identified significant associations at the ABO gene locus with risk of pancreatic cancer, but the influence of specific ABO genotypes remains unknown. We determined ABO genotypes (OO, AO, AA, AB, BO, and BB) in 1,534 cases and 1,583 controls from 12 prospective cohorts in PanScan, grouping participants by genotype-derived serologic blood type (O, A, AB, and B)....
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