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Article

Cell death and life in cancer: mathematical modeling of cell fate decisions.

Advances in experimental medicine and biology - 1 Jan 2012

Zinovyev Andrei, Fourquet Simon, Tournier Laurent, Calzone Laurence, Barillot Emmanuel

Abstract excerpt

Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tightly regulated in normal cells. Understanding this process provides insights for developing new treatments for fighting with cancer. We present a study of a mathematical model describing cellular choice between survival and two alternative cell death modalities: apoptosis and necrosis. The...

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PMID: 22161334
DOI: 10.1007/978-1-4419-7210-1_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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