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Article

Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci.

Journal of human genetics - 1 Feb 2012

Svenningsson Anna, Söderhäll Cilla, Persson Sofia, Lundberg Fredrik, Luthman Holger, Chung Eddie, Gardiner Mark, Kockum Ingrid, Nordenskjöld Agneta

Abstract excerpt

Infantile hypertrophic pyloric stenosis (IHPS) is a common cause of upper gastrointestinal obstruction during infancy. A multifactorial background of the disease is well established. Multiple susceptibility loci including the neuronal nitric oxide synthase (NOS1) gene have previously been linked to IHPS, but contradictory results of linkage studies in different materials indicate genetic heterogeneity. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22158425
DOI: 10.1038/jhg.2011.137

Genes

NPL
NOS1
NPY
GCG
MLN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci.PMID 22158425Read ↗

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