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Article

Genomic variants in the coding region of neuronal nitric oxide synthase (NOS1) in infantile hypertrophic pyloric stenosis.

Journal of pediatric surgery - 1 Oct 2011

Serra Alexandre, Schuchardt Katrin, Genuneit Jon, Leriche Clothilde, Fitze Guido

Abstract excerpt

BACKGROUND: Infantile hypertrophic pyloric stenosis (IHPS) is a common childhood pathology affecting 1 to 5:1000 newborns, with a genetic background suggested by familial occurrence. Neuronal nitric oxide synthase (NOS1) is a candidate gene owing to its role in the relaxation of smooth musculature and the association of the -84g>a variant of NOS1 with IHPS. METHODS: We investigated NOS1 through sequencing of the...

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Identifiers

PMID: 22008325
DOI: 10.1016/j.jpedsurg.2011.05.021

Genes

NOS1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genomic variants in the coding region of neuronal nitric oxide synthase (NOS1) in infantile hypertrophic pyloric stenosis.PMID 22008325Read ↗

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