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Article

Infantile hypertrophic pyloric stenosis: evaluation of three positional candidate genes, TRPC1, TRPC5 and TRPC6, by association analysis and re-sequencing.

Human genetics - 1 Dec 2009

Everett Kate V, Chioza Barry A, Georgoula Christina, Reece Ashley, Gardiner R Mark, Chung Eddie M K

Abstract excerpt

Infantile hypertrophic pyloric stenosis (IHPS) is the most common inherited form of gastrointestinal obstruction in infancy with a striking male preponderance. Infants present with vomiting due to gastric outlet obstruction caused by hypertrophy of the smooth muscle of the pylorus. Two loci speci...

Read the complete abstract on PubMed

Topics

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Share to TRPC6 gene
Share to Genetic Linkage
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Share to TRPC Cation Channels

Share to TRPC6 Cation Channel

Source

Identifiers

PMID: 19701773
DOI: 10.1007/s00439-009-0735-5

Genes

TRPC6
TRPC1
TRPC5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19701773-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Infantile hypertrophic pyloric stenosis: evaluation of three positional candidate genes, TRPC1, TRPC5 and TRPC6, by association analysis and re-sequencing.PMID 19701773Read ↗

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