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Article

Lack of association between nNOS -84G>A polymorphism and risk of infantile hypertrophic pyloric stenosis in a Chinese population.

Journal of pediatric surgery - 1 Apr 2010

Miao Xiaoping, Garcia-Barceló Maria-Mercè, So Man-ting, Tang Wai-kiu, Dong Xiao, Wang Bin, Mao Jianxiong, Ngan Elly Sau-wai, Chen Yan, Lui Vincent Chi-hang, Wong Kenneth Kak-yuen, Liu Lei, Tam Paul Kwong-hang

Abstract excerpt

BACKGROUND: Infantile hypertrophic pyloric stenosis (IHPS) is one of the most common gastrointestinal obstructions in the infancy requiring surgery. Reduced expression of neuronal nitric oxide synthase (nNOS), which plays an important role in the regulation of the human pyloric muscle, is thought to underlie IHPS. The role of nNOS in IHPS has been supported by the genetic association of a functional regulatory...

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PMID: 20385275
DOI: 10.1016/j.jpedsurg.2009.07.067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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