Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23.

American journal of human genetics - 1 Mar 2008

Everett Kate V, Chioza Barry A, Georgoula Christina, Reece Ashley, Capon Francesca, Parker Keith A, Cord-Udy Cathy, McKeigue Paul, Mitton Sally, Pierro Agostino, Puri Prem, Mitchison Hannah M, Chung Eddie M K, Gardiner R Mark

Abstract excerpt

Infantile hypertrophic pyloric stenosis (IHPS) has an incidence of 1-8 per 1000 live births and is inherited as a complex sex-modified multifactorial trait with a striking male preponderance. Syndromic and monogenic forms exist, and two loci have been identified. Infants present with vomiting due...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Genome, Human

Share to Infant

Share to Pedigree

Share to Polymorphism, Single Nucleotide

Share to Sex Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 18308288
DOI: 10.1016/j.ajhg.2007.12.023
PMCID: PMC2427303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18308288-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide high-density SNP-based linkage analysis of infantile hypertrophic pyloric stenosis identifies loci on chromosomes 11q14-q22 and Xq23.PMID 18308288Read ↗

Infantile hypertrophic pyloric stenosis: evaluation of three positional candidate genes, TRPC1, TRPC5 and TRPC6, by association analysis and re-sequencing.Semantic proximity Read ↗

Plasma lipids, genetic variants near APOA1, and the risk of infantile hypertrophic pyloric stenosis.Semantic proximity Read ↗

Genome-wide meta-analysis identifiesBARX1andEML4-MTA3as new loci associated with infantile hypertrophic pyloric stenosisSemantic proximity Read ↗

Infantile hypertrophic pyloric stenosis--genetics and syndromes.Semantic proximity Read ↗

Confirmation of two novel loci for infantile hypertrophic pyloric stenosis on chromosomes 3 and 5.Semantic proximity Read ↗

Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.Semantic proximity Read ↗

Infantile hypertrophic pyloric stenosis: epidemiology, genetics, and clinical update.Semantic proximity Read ↗

Genome-wide linkage analysis in families with infantile hypertrophic pyloric stenosis indicates novel susceptibility loci.Semantic proximity Read ↗

New insights into the pathogenesis of infantile pyloric stenosis.Semantic proximity Read ↗

A novel missense mutation in the transcription factor FOXF1 cosegregating with infantile hypertrophic pyloric stenosis in the extended pedigree linked to IHPS5 on chromosome 16q24.Semantic proximity Read ↗

The role of RET genomic variants in infantile hypertrophic pyloric stenosis.Semantic proximity Read ↗

Models for infantile hypertrophic pyloric stenosis development in patients with esophageal atresiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.