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Article

Increased white matter integrity in the corpus callosum in subjects with high genetic loading for schizophrenia.

Progress in neuro-psychopharmacology & biological psychiatry - 27 Apr 2012

Kim Sung Nyun, Park Jun Sung, Jang Joon Hwan, Jung Wi Hoon, Shim Geumsook, Park Hye Yoon, Hwang Jae Yeon, Choi Chi-Hoon, Kang Do-Hyung, Lee Jong-Min, Kwon Jun Soo

Abstract excerpt

OBJECTIVE: White matter abnormalities in the corpus callosum (CC) of schizophrenia have been reported to predate the illness onset. This study aimed to investigate the effect of genetic predisposition on the white matter integrity of the CC, in subjects at genetically high risk for schizophrenia (GHR) and schizophrenia patients. METHOD: Fractional anisotropy (FA) of the mid-sagittal CC in 22 young GHR, 15...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22155177
DOI: 10.1016/j.pnpbp.2011.11.015

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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