Article
A diffusion tensor MRI study of white matter integrity in subjects at high genetic risk of schizophrenia.
Schizophrenia research - 1 Dec 2008
Muñoz Maniega S, Lymer G K S, Bastin M E, Marjoram D, Job D E, Moorhead T W J, Owens D G, Johnstone E C, McIntosh A M, Lawrie S M
Abstract excerpt
Diffusion tensor imaging (DTI) has previously shown compromised white matter integrity in frontotemporal white matter fibers in patients with schizophrenia, as indicated by reduced fractional anisotropy (FA). In the present study we investigated whether reduced white matter FA is also present in relatives of individuals with schizophrenia who are at high risk (HR) for genetic reasons. Twenty-two HR subjects, 31...
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