Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphisms and surface expression of CTLA-4 and PD-1 on T cells of silica-exposed workers.

International journal of hygiene and environmental health - 1 Nov 2012

Rocha Michelle C, Santos Leonilda M B, Bagatin Ericson, Cohen Tervaert Jan W, Damoiseaux Jan G M C, Lido Alessandro V, Longhini Ana L, Torello Cristiane O, Queiroz Mary L S

Abstract excerpt

Exposure to silica dust has been examined as a possible risk factor for autoimmune diseases, including scleroderma, rheumatoid arthritis and systemic lupus erythematosus. Since CTLA-4 [CD152] and PD-1 [CD279] are important for the maintenance of peripheral tolerance by regulating T cell responsiveness, we evaluated the expression of these molecules on the surface of CD4 and CD8 T cells, as well as single...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to CD4 Lymphocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CTLA-4 Antigen

Share to Flow Cytometry

Share to Occupational Exposure

Share to Programmed Cell Death 1 Receptor

Share to Silicon Dioxide

Share to T-Lymphocytes

Source

Identifiers

PMID: 22153879
DOI: 10.1016/j.ijheh.2011.10.010

Genes

PDCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphisms and surface expression of CTLA-4 and PD-1 on T cells of silica-exposed workers.PMID 22153879Read ↗

Genetic variability of immune checkpoints in asbestos-related diseases.Semantic proximity Read ↗

Ambient PM exposure and DNA methylation in tumor suppressor genes: a cross-sectional studySemantic proximity Read ↗

Evaluation of +49 A>G (rs231775) Variant in CTLA4 Gene and SCTLA-4 Serum Levels in Plaque Psoriasis in a Mestizo Mexican Population.Semantic proximity Read ↗

Association of CTLA-4 but not CD28 gene polymorphisms with systemic lupus erythematosus in the Japanese population.Semantic proximity Read ↗

TNF-α and IL-1RA polymorphisms and silicosis susceptibility in Chinese workers exposed to silica particles: a case-control study.Semantic proximity Read ↗

Distribution of the CTLA-4 single nucleotide polymorphisms CT60G>A and +49A>G in psoriasis vulgaris patients and control individuals from a Polish Caucasian population.Semantic proximity Read ↗

CTLA-4 gene polymorphisms and natural soluble CTLA-4 protein in psoriasis vulgaris.Semantic proximity Read ↗

[FEATURES OF THE IMMUNE GENETIC PARAMETERS IN WORKERS IN NON-FERROUS METAL INDUSTRY].Semantic proximity Read ↗

[Polymorphisms of FAS and FASL genes and susceptibility of silicosis].Semantic proximity Read ↗

CTLA4 polymorphism in Spanish patients with systemic lupus erythematosus.Semantic proximity Read ↗

Assessment of Immunotoxicity Parameters in Individuals Occupationally Exposed to LeadSemantic proximity Read ↗

Lymphopenia in occupational pulmonary silicosis with or without autoimmune disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.