Article

IGFBP2 protects against pulmonary fibrosis through inhibiting P21-mediated senescence

2021-01-22

Abstract excerpt

Accumulation of senescent cells contributes to age related diseases including idiopathic pulmonary fibrosis (IPF). Insulin-like growth factor binding proteins (IGFBPs) are evolutionarily conserved proteins that play a vital role in many biological processes. Overall, little is known about the functions of IGFBP2 in the epigenetic regulation of cellular senescence and pulmonary fibrosis. Here, we show that Igfbp2...

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Literature Corpus work: 5f4acd1d-3131-5d80-b701-a3880864f9aa
DOI: 10.1101/2021.01.21.427684

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