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Article

Differential sensitivity to life stress in FMR1 premutation carrier mothers of children with fragile X syndrome.

Health psychology : official journal of the Division of Health Psychology, American Psychological Association - 1 Sept 2012

Seltzer Marsha Mailick, Barker Erin T, Greenberg Jan S, Hong Jinkuk, Coe Christopher, Almeida David

Abstract excerpt

OBJECTIVE: The premutation of the FMR1 gene (defined as between 55 and 200 CGG repeats) is estimated to affect 1 in 149 females and 1 in 643 males, and some people who carry the FMR1 premutation display signs of impairment. METHOD: This study focuses on 82 premutation carrier mothers (M age = 51.4 years; SD = 7.7) of adolescent and adult children with fragile X syndrome (FXS). A Gene × Environment interaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

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Source

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Identifiers

PMID: 22149120
DOI: 10.1037/a0026528
PMCID: PMC3434309

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential sensitivity to life stress in FMR1 premutation carrier mothers of children with fragile X syndrome.PMID 22149120Read ↗

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20-75 Years of Age.Semantic proximity Read ↗

Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms.Semantic proximity Read ↗

Mood and anxiety disorders in females with the FMR1 premutation.Semantic proximity Read ↗

Family as a Context for Child Development: Mothers with the FMR1 Premutation and Their Children with Fragile X Syndrome.Semantic proximity Read ↗

Investigation of phenotypes associated with mood and anxiety among male and female fragile X premutation carriers.Semantic proximity Read ↗

Child and genetic variables associated with maternal adaptation to fragile X syndrome: a multidimensional analysis.Semantic proximity Read ↗

Psychological status in female carriers of premutation FMR1 allele showing a complex relationship with the size of CGG expansion.Semantic proximity Read ↗

Inhibition deficits are modulated by age and CGG repeat length in carriers of the FMR1 premutation allele who are mothers of children with fragile X syndrome.Semantic proximity Read ↗

FMR1 genotype interacts with parenting stress to shape health and functional abilities in older age.Semantic proximity Read ↗

High rates of comorbid depressive and anxiety disorders among women with premutation of the FMR1 gene.Semantic proximity Read ↗

Evidence of depressive symptoms in fragile-X syndrome premutated females.Semantic proximity Read ↗

Curvilinear association of CGG repeats and age at menopause in women with FMR1 premutation expansions.Semantic proximity Read ↗

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