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Article

Investigation of phenotypes associated with mood and anxiety among male and female fragile X premutation carriers.

Behavior genetics - 1 Sept 2008

Hunter Jessica Ezzell, Allen Emily Graves, Abramowitz Ann, Rusin Michele, Leslie Mary, Novak Gloria, Hamilton Debra, Shubeck Lisa, Charen Krista, Sherman Stephanie L

Abstract excerpt

The fragile X disorder spectrum, due to a CGG expansion in FMR1, includes fragile X syndrome (>200 repeats) and the premutation-associated disorders of ovarian insufficiency and tremor/ataxia syndrome (approximately 55-199 repeats). Altered neurobehavioral profiles including variation of phenotypes associated with mood and anxiety may be expected among younger premutation carriers given this spectrum of...

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Identifiers

PMID: 18535897
DOI: 10.1007/s10519-008-9214-3
PMCID: PMC3696488

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Investigation of phenotypes associated with mood and anxiety among male and female fragile X premutation carriers.PMID 18535897Read ↗

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Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers.Semantic proximity Read ↗

Health problems in females carriers of premutation in the FMR1 gene.Semantic proximity Read ↗

Indicators of anxiety and depression in women with the fragile X premutation: assessment of a clinical sampleSemantic proximity Read ↗

Fragile X premutation in women: recognizing the health challenges beyond primary ovarian insufficiency.Semantic proximity Read ↗

Abnormal elevation of FMR1 mRNA is associated with psychological symptoms in individuals with the fragile X premutation.Semantic proximity Read ↗

A review of fragile X premutation disorders: expanding the psychiatric perspective.Semantic proximity Read ↗

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Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20-75 Years of Age.Semantic proximity Read ↗

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