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Article

VEGFA Family Isoforms Regulate Spermatogonial Stem Cell Homeostasis in Vivo

7 Dec 2011

Abstract excerpt

The objective of the present study was to investigate vascular endothelial growth factor A (VEGFA) isoform regulation of cell fate decisions of spermatogonial stem cells (SSC) in vivo. The expression pattern and cell-specific distribution of VEGF isoforms, receptors, and coreceptors during testis development postnatal d 1-180 suggest a nonvascular function for VEGF regulation of early germ cell homeostasis....

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PMID: 22147017
DOI: 10.1210/en.2011-1323

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