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Article

Aged PROP1 deficient dwarf mice maintain ACTH production.

PloS one - 1 Jan 2011

Nasonkin Igor O, Ward Robert D, Bavers David L, Beuschlein Felix, Mortensen Amanda H, Keegan Catherine E, Hammer Gary D, Camper Sally A

Abstract excerpt

Humans with PROP1 mutations have multiple pituitary hormone deficiencies (MPHD) that typically advance from growth insufficiency diagnosed in infancy to include more severe growth hormone (GH) deficiency and progressive reduction in other anterior pituitary hormones, eventually including adrenocorticotropic hormone (ACTH) deficiency and hypocortisolism. Congenital deficiencies of GH, prolactin, and thyroid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22145038
DOI: 10.1371/journal.pone.0028355
PMCID: PMC3228747

Genes

PROP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Aged PROP1 deficient dwarf mice maintain ACTH production.PMID 22145038Read ↗

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The Effects of Growth Hormone (GH) Treatment on GH and Insulin/IGF-1 Signaling in Long-Lived Ames Dwarf MiceSemantic proximity Read ↗

Impaired Adrenocorticotropin-Adrenal Axis in Combined Pituitary Hormone Deficiency Caused by a Two-Base Pair Deletion (301–302delAG) in the Prophet of Pit-1 Gene<sup>1</sup>Semantic proximity Read ↗

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