Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells

1 Dec 2010

Abstract excerpt

UNLABELLED: Here we demonstrate that primary cultures of human fetal liver cells (HFLC) reliably support infection with laboratory strains of hepatitis C virus (HCV), although levels of virus replication vary significantly between different donor cell preparations and frequently decline in a manner suggestive of active viral clearance. To investigate possible contributions of the interferon (IFN) system to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis C virus research
Share to interferon and immune responses
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22144107
DOI: 10.1002/hep.24557

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cellsPMID 22144107Read ↗

Virus Replication in Engineered Human Cells That Do Not Respond to InterferonsSemantic proximity Read ↗

Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver culturesSemantic proximity Read ↗

Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during DifferentiationSemantic proximity Read ↗

Paramyxovirus strategies for evading the interferon responseSemantic proximity Read ↗

Paramyxovirus Accessory Proteins as Interferon AntagonistsSemantic proximity Read ↗

Naturally Occurring Substitutions in the P/V Gene Convert the Noncytopathic Paramyxovirus Simian Virus 5 into a Virus That Induces Alpha/Beta Interferon Synthesis and Cell DeathSemantic proximity Read ↗

Growth sensitivity of a recombinant simian virus 5 P/V mutant to type I interferon differs between tumor cell lines and normal primary cells.Semantic proximity Read ↗

Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus.Semantic proximity Read ↗

Cell entry, efficient RNA replication, and production of infectious hepatitis C virus progeny in mouse liver-derived cellsSemantic proximity Read ↗

Paramyxovirus-Induced Shutoff of Host and Viral Protein Synthesis: Role of the P and V Proteins in Limiting PKR ActivationSemantic proximity Read ↗

Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human CellsSemantic proximity Read ↗

Modeling of Human Cytomegalovirus Maternal-Fetal Transmission in a Novel Decidual Organ CultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.