Article
Mechanisms of resistance to chloramphenicol in Pseudomonas putida KT2440.
Antimicrobial agents and chemotherapy - 1 Feb 2012
Fernández Matilde, Conde Susana, de la Torre Jesús, Molina-Santiago Carlos, Ramos Juan-Luis, Duque Estrella
Abstract excerpt
Pseudomonas putida KT2440 is a chloramphenicol-resistant bacterium that is able to grow in the presence of this antibiotic at a concentration of up to 25 μg/ml. Transcriptomic analyses revealed that the expression profile of 102 genes changed in response to this concentration of chloramphenicol in the culture medium. The genes that showed altered expression include those involved in general metabolism, cellular...
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