Article
Increased miRNA-146a and miRNA-155 expressions in oral lichen planus.
Archives of dermatological research - 1 Jul 2012
Arão Telma Cristina, Guimarães André Luiz Sena, de Paula Alfredo Maurício Batista, Gomes Carolina Cavaliéri, Gomez Ricardo Santiago
Abstract excerpt
Oral lichen planus (OLP) is a chronic inflammatory disease T helper 1 lymphocytes (Th1)-mediated. Interferon-gamma (IFN-γ) plays a central role in local immune response in this disease. MicroRNAs (miRNAs) are endogenously expressed non-coding RNAs that have important biological and pathological functions due to their potential mechanism regulating gene expression. Recently, some studies have demonstrated that...
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