Article
MiR-155-5p modulates inflammatory phenotype of activated oral lichen-planus-associated-fibroblasts by targeting SOCS1.
Molecular biology reports - 1 Aug 2022
Cheng Juehua, Zhang Yuyao, Yang Jingjing, Wang Yanting, Xu Juanyong, Fan Yuan
Abstract excerpt
BACKGROUND: Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disease. Cytokines are closely associated with OLP development. In addition to immune cells, fibroblasts have been reported to induce regional inflammation. MicroRNA(miR)-155-5p is reportedly increased significantly in OLP and is known to regulate inflammation. This study aimed to investigate the role of miR-155-5p in fibroblasts of OLP...
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