Article
Disease-associated miRNA-mRNA networks in oral lichen planus.
PloS one - 1 Jan 2013
Gassling Volker, Hampe Jochen, Açil Yahya, Braesen Jan Hinrich, Wiltfang Jörg, Häsler Robert
Abstract excerpt
BACKGROUND: A large number of pathophysiological mechanisms are regulated by microRNAs (miRNAs), which represent a new class of posttranscriptional regulators of gene expression. To date, little is known about their role in oral lichen planus (OLP), a chronic inflammatory mucocutaneous disease of unknown etiology which is being discussed as a potentially premalignant condition of oropharyngeal cancer. The aim of...
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