Article
Frequency of HLA-DP-specific antibodies and a possible new cross-reacting group.
Human immunology - 1 Feb 2012
Callender Carly J, Fernandez-Vina Marcelo, Leffell Mary S, Zachary Andrea A
Abstract excerpt
Clinical studies have demonstrated that HLA-DP-specific antibodies can be detrimental to a transplanted kidney. The number of patients affected is proportional to the frequency of DP antibodies. We determined the frequency of HLA-DP-specific antibodies en toto and in the absence of cross-reactive DR antibodies. Of 650 waitlisted renal patients, 271 (42%) were reactive with HLA-DP antigens in solid-phase...
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