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Article

Lymphangiogenesis is required for pancreatic islet inflammation and diabetes.

PloS one - 1 Jan 2011

Yin Na, Zhang Nan, Lal Girdhari, Xu Jiangnan, Yan Minhong, Ding Yaozhong, Bromberg Jonathan S

Abstract excerpt

Lymphangiogenesis is a common phenomenon observed during inflammation and engraftment of transplants, but its precise role in the immune response and underlying mechanisms of regulation remain poorly defined. Here we showed that in response to injury and autoimmunity, lymphangiogenesis occurred around islets and played a key role in the islet inflammation in mice. Vascular endothelial growth factors receptor 3...

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Identifiers

PMID: 22132197
DOI: 10.1371/journal.pone.0028023
PMCID: PMC3223214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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