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Article

Association between polymorphisms of XRCC1, p53 and MDR1 genes, the expression of their protein products and prognostic significance in human breast cancer.

Medical science monitor : international medical journal of experimental and clinical research - 1 Dec 2011

Rybárová Silvia, Vecanová Janka, Hodorová Ingrid, Mihalik Jozef, Čižmáriková Martina, Mojžiš Ján, Solár Peter, Benický Marián, Adamkov Marian, Mirossay Ladislav

Abstract excerpt

BACKGROUND: This study aimed to examine the relationship between XRCC1, p53 and MDR1 protein, along with polymorphisms of their genes and their prognostic values in breast cancer. The following clinical and pathological parameters were evaluated: histopathological type of tumor, grade, stage, Her2/neu expression, ER, PR positivity and involvement of regional lymph nodes. MATERIAL/METHODS: Expression of proteins...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Ductal, Breast

Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 22129893
DOI: 10.12659/msm.882121
PMCID: PMC3628133

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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