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Article

G<scp>ENETIC</scp>E<scp>FFECTS OF</scp>M<scp>ETHYLATION</scp>D<scp>IETS</scp>

1 Jul 2002

Abstract excerpt

DNA methylation at cytosines in CpG dinucleotides can lead to changes in gene expression and function without altering the primary sequence of the DNA. Methylation can be affected by dietary levels of methyl-donor components, such as folic acid. This may be an important mechanism for environmentally induced changes in gene expression. Recent literature supports a role for DNA-methylation changes in a number of...

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PMID: 12055346
DOI: 10.1146/annurev.nutr.22.010402.102932

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