Article
LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's disease.
Behavioural brain research - 17 Mar 2012
Fernández-Fernández Laura, Comes Gemma, Bolea Irene, Valente Tony, Ruiz Jessica, Murtra Patricia, Ramirez Bartolomé, Anglés Neus, Reguant Jordi, Morelló José Ramón, Boada Mercè, Hidalgo Juan, Escorihuela Rosa María, Unzeta Mercedes
Abstract excerpt
We examined whether LMN diet, reported to induce neurogenesis in adult mice, was able to antagonize the age-related behavioural impairment and neuropathology in wild type (WT) mice and Tg2576 mice, a mouse model of Alzheimer's disease (AD). Thirteen-month-old mice (once the amyloid (Aβ) plaques w...
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