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Article

Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Hutton Craig P, Lemon Jennifer A, Sakic Boris, Rollo C David, Boreham Douglas R, Fahnestock Margaret, Wojtowicz J Martin, Becker Suzanna

Abstract excerpt

The increasing global burden of Alzheimer's disease (AD) and failure of conventional treatments to stop neurodegeneration necessitates an alternative approach. Evidence of inflammation, mitochondrial dysfunction, and oxidative stress prior to the accumulation of amyloid-β in the prodromal stage of AD (mild cognitive impairment; MCI) suggests that early interventions which counteract these features, such as...

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PMID: 29914019
DOI: 10.3233/JAD-170921

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