Article
Developmental expression and organisation of fibrinogen genes in the zebrafish.
Thrombosis and haemostasis - 1 Jan 2012
Fish Richard J, Vorjohann Silja, Béna Frédérique, Fort Alexandre, Neerman-Arbez Marguerite
Abstract excerpt
The zebrafish is a model organism for studying vertebrate development and many human diseases. Orthologues of the majority of human coagulation factors are present in zebrafish, including fibrinogen. As a first step towards using zebrafish to model human fibrinogen disorders, we cloned the zebrafish fibrinogen cDNAs and made in situ hybridisations and quantitative reverse transcription-polymerase chain reactions...
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