Article
A factor in a wild isolated Neurospora crassa strain enables a chromosome segment duplication to suppress repeat-induced point mutation.
Journal of biosciences - 1 Dec 2011
Ramakrishnan Mukund, Sowjanya T Naga, Raj Kranthi B, Kasbekar Durgadas P
Abstract excerpt
Repeat-induced point mutation (RIP) is a sexual stage-specific mutational process of Neurospora crassa and other fungi that alters duplicated DNA sequences. Previous studies from our laboratory showed that chromosome segment duplications (Dps) longer than (approx.) 300 kbp can dominantly suppress RIP, presumably by titration of the RIP machinery, and that although Dps less than 200 kbp did not individually...
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