Article
Translocations used to generate chromosome segment duplications in Neurospora can disrupt genes and create novel open reading frames.
Journal of biosciences - 1 Dec 2010
Singh Parmit K, Iyer Srividhya V, Sowjanya T Naga, Raj B Kranthi, Kasbekar Durgadas P
Abstract excerpt
In Neurospora crassa, crosses between normal sequence strains and strains bearing some translocations can yield progeny bearing a duplication (Dp) of the translocated chromosome segment. Here, 30 breakpoint junction sequences of 12 Dp-generating translocations were determined. The breakpoints disrupted 13 genes (including predicted genes), and created 10 novel open reading frames. Insertion of sequences from LG...
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